Entamoeba histolytica Project

Hit Summary

April to August 2006, screen of 2160 compound Microsource library (FDA and natural product drugs) against Entamoeba histolytica.

A hit is defined as a compound that results in ~>90% growth inhibition at 1 micromolar concentration. 

Structures
CommonName
SupplierID
Salt
CAS
Therapy

Effective
Concentration

%
inhibittion
phenylmercuric acetate
1500644
NONE
62-38-4
fungicide
1 µM
63
cycloheximide
1502112
NONE
66-81-9
protein
synthesis
inhibitor
1 µM
99
Acetochlor
330089
NONE
herbicide, cell division inhibitorbitor
1 µM
98